However, it is important that you make sure that it will protect you from the malaria parasites endemic to the region you are travelling to. The dose of chloroquine and proguanil depends on your body weight.
The standard dose for adults over 45kg is two tablets mg base of chloroquine and 2 tablets mg of proguanil. If you are unsure, speak to a nurse or pharmacist who will be able to advise on the correct dose for you. Start taking chloroquine one week before entering the malaria risk area.
For proguanil it is sufficient to start taking the tablets 2 days before entering the risk area. You need to take the prescribed dose of chloroquine once every week on the same day; proguanil should be taken once every day. You should take the tablets after a meal and swallow them whole with water. For young children or those who cannot swallow, the tablets can be crushed and added to milk, honey or jam.
For a full list of all risk and side effects associated with chloroquine and proguanil read the patient information leaflet. Travel Vaccinations. During your appointment, the nurse or pharmacist will assess which vaccines or medications you need. Generic filters Hidden label.
Hidden label. Call to book Find your nearest clinic. Book an appointment now. About the tablets Dosage : The standard dose for adults over 45kg is two tablets of Chloroquine and 2 tablets of Proguanil. For Proguanil it is sufficient to start taking the tablets 2 days before entering the risk area. You need to take the prescribed dose of Chloroquine once every week on the same day; Proguanil should be taken once every day.
What is chloroquine?
Continue taking Chloroquine and Proguanil until four weeks after leaving the malaria area. Side effects: As with most medications, side effects can occur in some patients. Possible side effects include rash, digestive problems, headache or an allergic reaction. Who can take it? Chloroquine and Proguanil will be suitable for most people provided it is effective in the country you are travelling to.
However, it is not suitable for everyone so a healthcare professional needs to assess whether it is safe for you, taking into account important factors like your medical history and any current medications. Low body wt: use children's dose. Prophylaxis: 8. Treatment: Prophylaxis: start 2 weeks before and continue for 8 weeks after trip. Monitor for cardiomyopathy esp. Cardiac disease. History of ventricular arrhythmias.
Drugs (generic and trade name) for the treatment and prevention of malaria
Monitor for hypoglycemia. Macular disease. Perform baseline eye exam within the first year of initiation, then annually.
Avoid in psoriasis, porphyria. Discontinue if muscular weakness, ocular toxicity, or hearing defects occur.
Hepatic, renal, or auditory dysfunction. Seizure disorders.
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G6PD deficiency. Monitor CBC, reflexes in long-term use. Pregnancy use adequate contraception in endemic areas. Nursing mothers: not recommended. Avoid cimetidine. Retinal toxicity with concomitant tamoxifen: not recommended. May potentiate insulin and other antidiabetic drugs: decrease doses of these. Separate ampicillin dose by 2hrs; dosing of antacids or kaolin by 4hrs.